Sanofi, Regeneron in COVID-19 Pact

Begin global Kevzara (sarilumab) clinical trial program in patients with severe COVID-19

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By: Tim Wright

Editor-in-Chief, Contract Pharma

Sanofi and Regeneron Pharmaceuticals have started a clinical program evaluating Kevzara (sarilumab) in patients hospitalized with severe COVID-19. Kevzara is a fully-human monoclonal antibody that inhibits the interleukin-6 (IL-6) pathway by binding and blocking the IL-6 receptor. IL-6 may play a role in driving the overactive inflammatory response in the lungs of patients who are severely or critically ill with COVID-19 infection. The role of IL-6 is supported by preliminary data from a single-...

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